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Genome Analysis of Shigella flexneri Serotype 3b Strain SFL1520 Reveals Significant Horizontal Gene Acquisitions Including a Multidrug Resistance Cassette

Parajuli, Pawan; Deimel, Lachlan; Verma, Naresh

Description

Shigella flexneri is a major etiological agent of shigellosis in developing countries, primarily occurring in children under 5 years of age. We have sequenced, for the first time, the complete genome of S. flexneri serotype 3b (strain SFL1520). We used a hybrid sequencing method––both long-read MinION Flow (Oxford Nanopore Technologies) and short-read MiSeq (Illumina) sequencing to generate a high-quality reference genome. The SFL1520 chromosome was found to be ∼4.58 Mb long, with 4,729 coding...[Show more]

CollectionsANU Research Publications
Date published: 2019-02-01
Type: Journal article
URI: http://hdl.handle.net/1885/188495
Source: Genome Biology and Evolution
DOI: 10.1093/gbe/evz026
Access Rights: Open Access

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