Identification and Characterization of gamma-Glutamylamine Cyclotransferase, an Enzyme Responsible for gamma-Glutamyl-epsilon-lysine Catabolism
Date
2010
Authors
Oakley, Aaron
Coggan, Marjorie
Board, Philip
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American Society for Biochemistry and Molecular Biology Inc
Abstract
γ-Glutamylamine cyclotransferase (GGACT) is an enzyme that converts γ-glutamylamines to free amines and 5-oxoproline. GGACT shows high activity toward γ-glutamyl-ε-lysine, derived from the breakdown of fibrin and other proteins cross-linked by transgl
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Keywords: Active site; Different substrates; Enzymatic activities; Free amines; High activity; Sequence identity; Three-dimensional structure; Transglutaminases; Amination; Amino acids; Catalysts; Enzymes; Organic acids; Plants (botany); Enzyme activity; 6 (gamma g
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Source
Journal of Biological Chemistry
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Journal article
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2037-12-31
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