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Hypoxia-Induced MicroRNA-210 Targets Neurodegenerative Pathways

Watts, Michelle E.; Williams, Sarah M.; Nithianantharajah, Jess; Claudianos, Charles

Description

Hypoxia-regulated microRNA-210 (miR-210) is a highly conserved microRNA, known to regulate various processes under hypoxic conditions. Previously we found that miR-210 is also involved in honeybee learning and memory, raising the questions of how neural activity may induce hypoxia-regulated genes and how miR-210 may regulate plasticity in more complex mammalian systems. Using a pull-down approach, we identified 620 unique target genes of miR-210 in humans, among which there was a significant...[Show more]

CollectionsANU Research Publications
Date published: 2018-03-27
Type: Journal article
URI: http://hdl.handle.net/1885/173707
Source: Non-Coding RNA
DOI: 10.3390/ncrna4020010
Access Rights: Open Access

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