Risperidone, haloperidol and placebo in the treatment of aggressive challenging behaviour in intellectual disability: randomised controlled trial
-
Altmetric Citations
Tyrer, Peter; Oliver-Africano, Patricia C; Ahmed, Zed; Bouras, Nick; Cooray, Sherva; Deb, Shoumitro; Murphy, Declan; Hare, Monica; Meade, Michael; Reece, Ben; Kramo, Kofi; Bhaumik, Sabyasachi; Harley, David; Regan, Adrienne; Thomas, David; Rao, Bharti; North, Bernard; Eliahoo, Joseph; Karatela, Shamshad; Soni, Anju; Crawford, Mike
Description
Background: Aggressive challenging behaviour is frequently reported in adults with intellectual disability and it is often treated with antipsychotic drugs. However, no adequate evidence base for this practice exists. We compared flexible doses of haloperidol (a typical, first-generation antipsychotic drug), risperidone (an atypical, second-generation antipsychotic), and placebo, in the treatment of this behaviour. Methods: 86 non-psychotic patients presenting with aggressive challenging...[Show more]
Collections | ANU Research Publications |
---|---|
Date published: | 2008 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/17245 |
Source: | Lancet, The (UK edition) |
DOI: | 10.1016/S0140-6736(08)60072-0 |
Download
File | Description | Size | Format | Image |
---|---|---|---|---|
01_Tyrer_Risperidone,_haloperidol_and_2008.pdf | 143.38 kB | Adobe PDF | Request a copy |
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 17 November 2022/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator