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VHA-19 is essential in Caenorhabditis elegans oocytes for embryogenesis and is involved in trafficking in oocytes

Knight, Alison J.; Johnson, Nicholas M.; Behm, Carolyn A.

Description

There is an urgent need to develop new drugs against parasitic nematodes, which are a significant burden on human health and agriculture. Information about the function of essential nematode-specific genes provides insight to key nematode-specific processes that could be targeted with drugs. We have characterized the function of a novel, nematode-specific Caenorhabditis elegans protein, VHA-19, and show that VHA-19 is essential in the germline and, specifically, the oocytes, for the completion...[Show more]

CollectionsANU Research Publications
Date published: 2012-07-02
Type: Journal article
URI: http://hdl.handle.net/1885/16625
Source: PLoS ONE
DOI: 10.1371/journal.pone.0040317

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