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Photopolymerizable thiol-acrylate maleiated hyaluronic acid/thiol-terminated poly(ethylene glycol) hydrogels as potential in-situ formable scaffolds

Zhang, Can; Dong, Qi; Liang, Kaili; Ding, Zhou; Yang, Hongjun; Liu, Xiu; Xu, Weilin; Zhou, Yingshan; Xiao, Pu


Despite their potential in various biomedical applications, photocrosslinkable hyaluronate hydrogels have often been limited by weak formation and unsatisfied mechanical strength which can be attributed to insufficient substitution of photoactive groups on the hyaluronate backbone and the oxygen inhibition effect. In this study, a new approach for the production of hyaluronic acid (MHA) with high acrylate group substitution (i.e. 2.27) is developed. It is based on the reaction of sodium...[Show more]

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
Source: International Journal of Biological Macromolecules
DOI: 10.1016/j.ijbiomac.2018.07.153


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