Scrub Typhus in mainland China, 2006–2012: the need for targeted public health interventions
Date
2013-12-26
Authors
Zhang, Wen-Yi
Wang, Li-Ya
Ding, Fan
Hu, Wen-Biao
Soares Magalhaes, Ricardo
Sun, Hai-Long
Liu, Yun-Xi
Liu, Qi-Yong
Huang, Liu-Yu
Clements, Archie C. A.
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Public Library of Science
Abstract
Scrub typhus is a vector-borne disease
carried by the chigger mite. The aetiological
agent is the rickettsia Orientia
tsutsugamushi, which is endemic to several
countries in the Asia-Pacific region,
including China [1]. It is also a travel associated
disease [2] and of great importance
among military personnel [3,4].
During the Second World War, scrub
typhus was associated with a higher case
fatality ratio than any other infectious
disease in the China-Burma-India theatre
of operations [1,3]. Clinical presentation
in patients varies from asymptomatic
to life-threatening disease [5], including
acute hearing loss and multiple organ
failure [6,7]. To date, there is still no
effective and reliable human vaccine
against scrub typhus and no point-of-care
diagnostics available [1].
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Keywords
china, communicable disease control, humans, public health administration, scrub typhus, spatio-temporal analysis, topography, medical
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PLoS Neglected Tropical Diseases
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Journal article
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