Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits
Most organisms exhibit senescence; a decline in physiological function with age. In nature, rates of senescence vary extensively among individuals and this variation has a significant genetic component; however, we know little about the genes underlying senescence. Here we show the first evidence that individual alleles influence fecundity in an age-specific manner and so the genetic basis of natural variation in fecundity changes dramatically with age. We complete a genome-wide association to...[Show more]
|Collections||ANU Research Publications|
|Access Rights:||Open Access|
|01_Durham_Genome-wide_analysis_in_2014.pdf||1.01 MB||Adobe PDF|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.