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A systematic review and meta-analysis of longitudinal hippocampal atrophy in healthy human ageing

Fraser, Mark; Shaw, Marnie E.; Cherbuin, Nicolas


INTRODUCTION: This review aimed to produce hippocampal atrophy rate estimates from healthy ageing studies as well as control samples from observational studies across the adult lifespan which can be used as benchmarks to evaluate abnormal changes in pathological conditions. METHODS: The review followed PRISMA guidelines. PUBMED (to February 2014) was searched for longitudinal MRI studies reporting hippocampal atrophy or volume change in cognitively healthy individuals. Titles were screened and...[Show more]

CollectionsANU Research Publications
Date published: 2015-05-15
Type: Journal article
Source: NeuroImage
DOI: 10.1016/j.neuroimage.2015.03.035


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