Keyhole limpet haemocyanin – a model antigen for human immunotoxicological studies
Immunization with a T-cell dependent antigen has been promoted as a reliable and sensitive tool for assessing the influence of putative immunotoxic exposures or agents on immune function. Keyhole limpet haemocyanin (KLH) is a very large, copper-containing protein molecule derived from the haemolymph of the inedible mollusc, Megathura crenulata. KLH is a highly immunogenic T-cell dependent antigen that is used increasingly in immunotoxicological studies, particularly in those involving animals....[Show more]
|Collections||ANU Research Publications|
|Source:||British Journal of Clinical Pharmacology 78.5 (2014): 1135–1142|
|Access Rights:||Open Access|
|Swaminathan et al 2014 Keyhole limpet haemocyanin.pdf||745.18 kB||Adobe PDF|
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