Skip navigation
Skip navigation

Enterocyte-specific regulation of the apical nutrient transporter SLC6A19 (B0AT1) by transcriptional and epigenetic networks

Tümer, Emrah; Bröer, Angelika; Balkrishna, Sarojini; Jülich, Torsten; Bröer, Stefan


Enterocytes are specialized to absorb nutrients from the lumen of the small intestine by expressing a select set of genes to maximize the uptake of nutrients. They develop from stem cells in the crypt and differentiate into mature enterocytes while moving along the crypt-villus axis. Using, as an example, the Slc6a19 gene, encoding the neutral amino acid transporter B0AT1, we studied regulation of the gene by transcription factors and epigenetic factors in the intestine. To investigate this...[Show more]

CollectionsANU Research Publications
Date published: 2013-10-11
Type: Journal article
Source: Journal of Biological Chemistry 288.47 (2013): 33813-23
DOI: 10.1074/jbc.M113.482760


File Description SizeFormat Image
Broer_Regulation_2013.pdf989.55 kBAdobe PDFThumbnail

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator