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Intestinal peptidases form functional complexes with the neutral amino acid transporter BᴼAT1

Fairweather, Stephen J; Bröer, Angelika; O’Mara, Megan L; Bröer, Stefan


The brush-border membrane of the small intestine and kidney proximal tubule are the major sites for the absorption and re-absorption of nutrients in the body respectively. Transport of amino acids is mediated through the action of numerous secondary active transporters. In the mouse, neutral amino acids are transported by BᴼAT1 [broad neutral (ᴼ) amino acid transporter 1; SLC6A19 (solute carrier family 6 member 19)] in the intestine and by BᴼAT1 and BᴼAT3 (SLC6A18) in the...[Show more]

CollectionsANU Research Publications
Date published: 2012-08-15
Type: Journal article
Source: Biochemical Journal 446. 1 (2012): 135-148
DOI: 10.1042/BJ20120307


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