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T-cell subsets in the germinal center

Ramiscal, Roybel R; Vinuesa, Carola G


T cells are known to migrate to B-cell-enriched follicles and germinal centers within secondary lymphoid organs to provide help to B cells. Cognate T:B interactions that take place at the T:B border and subsequently within germinal centers are essential for B-cell priming, differentiation into germinal center B cells, and selection of mutated cells into memory B cells or memory plasma cells. In recent years, different stages of maturation within B-cell helper T cells, collectively known as...[Show more]

CollectionsANU Research Publications
Date published: 2013-02-13
Type: Journal article
Source: Immunological Reviews 252.1 (2013): 146-155
DOI: 10.1111/imr.12031


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