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Gating Mechanism of Mechanosensitive Ion Channels Studied by Continuum Mechanics

Bavi, Navid; Nomura, Takeshi; Qin, Qinghua; Martinac, Boris

Description

To complement the existing experimental and computational methods used for studies of membrane protein structure and dynamics a finite element (FE) model for multi length-scale and time-scale investigations of the gating mechanism of mechanosensitive (MS) ion channels has been established. The main advantage of the FE simulation over molecular dynamic simulation is its flexibility in handling complex geometries and boundary conditions. In this study the FE model of MscL, the large conductance...[Show more]

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
URI: http://hdl.handle.net/1885/100884
Source: Biophysical Journal
DOI: 10.1016/j.bpj.2013.11.3085

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