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A publish-subscribe model of genetic networks

Calcott, Brett; Balcan, Duygu; Hohenlohe, Paul


We present a simple model of genetic regulatory networks in which regulatory connections among genes are mediated by a limited number of signaling molecules. Each gene in our model produces (publishes) a single gene product, which regulates the expression of other genes by binding to regulatory regions that correspond (subscribe) to that product. We explore the consequences of this publish-subscribe model of regulation for the properties of single networks and for the evolution of populations...[Show more]

CollectionsANU Research Publications
Date published: 2008-09-19
Type: Journal article
Source: PLOS ONE (Public Library of Science)
DOI: 10.1371/journal.pone.0003245


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