Skip navigation
Skip navigation

The evolution of imprinting: chromosomal mapping of orthologues of mammalian imprinted domains in monotreme and marsupial mammals

Edwards, Carol A; Rens, Willem; Clarke, Oliver; Mungall, Andrew J; Hore, Tim; Graves, Jennifer; Dunham, Ian; Ferguson-Smith, Anne C; Ferguson-Smith, Malcolm A

Description

BACKGROUND: The evolution of genomic imprinting, the parental-origin specific expression of genes, is the subject of much debate. There are several theories to account for how the mechanism evolved including the hypothesis that it was driven by the evolution of X-inactivation, or that it arose from an ancestrally imprinted chromosome. RESULTS: Here we demonstrate that mammalian orthologues of imprinted genes are dispersed amongst autosomes in both monotreme and marsupial...[Show more]

CollectionsANU Research Publications
Date published: 2007-09-06
Type: Journal article
URI: http://hdl.handle.net/10440/227
http://digitalcollections.anu.edu.au/handle/10440/227
Source: BMC Evolutionary Biology
DOI: 10.1186/1471-2148-7-157

Download

File Description SizeFormat Image
Edwards_Evolution2007.pdf753.2 kBAdobe PDFThumbnail


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  23 August 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator