Organometallic reagents primed for peptide modification
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Elgindy, Cecile
Malins, Lara R.
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Abstract
In this issue of Chem Catalysis, Walczak and co-workers introduce a carbastannatrane alanine derivative that facilitates amino acid side-chain functionalizations via C–C, C–S, and C–Se bond formation using Stille cross-coupling reactions. Applications in late-stage peptide modifications and macrocyclizations further exemplify the value of this novel building block.
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Chem Catalysis
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