Synthesis of gold-coated magnetic conglomerate nanoparticles with a fast magnetic response for bio-sensing

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dc.contributor.authorMehdipour, Miladen
dc.contributor.authorGloag, Lucyen
dc.contributor.authorBennett, Danielle T.en
dc.contributor.authorHoque, Sharminen
dc.contributor.authorPardehkhorram, Rahelehen
dc.contributor.authorBakthavathsalam, Padmavathyen
dc.contributor.authorGoncales, Vinicius R.en
dc.contributor.authorTilley, Richard D.en
dc.contributor.authorGooding, J. Justinen
dc.date.accessioned2025-12-16T01:39:59Z
dc.date.available2025-12-16T01:39:59Z
dc.date.issued2020-12-08en
dc.description.abstractThe versatile qualities of gold coated magnetic nanoparticles for both optical and electrochemical detection, as well as the separation of analytes, make them an excellent choice for ultrasensitive biosensing applications. The challenge with such nanoparticles however is that strongly magnetic nanoparticles that reach the magnet rapidly are prone to aggregation, whilst superparamagnetic nanoparticles that are stable against aggregation reach the magnet slowly. Here, we report a conglomerate nanostructure consisting of superparamagnetic nanoparticles coated with gold that provides a rapid magnetic response while exhibiting colloidal stability in solution. The performance of these gold coated magnetic nanoparticles for both bio-separation and biosensing was demonstrated for application in biosensors, dispersible electrodes for detecting microRNA and surface-enhanced Raman scattering.en
dc.description.sponsorshipJJG and RDT acknowledge funding under the Australian Research Council Linkage grant (LP150101014), the Australian Laureate Fellowship (FT150100060), ARC Centre of Excellence in Convergent Bio-Nano Science and Technology (CE140100036) and the Discovery Project (DP190102659 and DP200100143). LG and RDT acknowledge the Dementia Australia Research Foundation Yulgilbar innovation grant.en
dc.description.statusPeer-revieweden
dc.format.extent10en
dc.identifier.issn2050-7534en
dc.identifier.otherWOS:000612717600029en
dc.identifier.otherORCID:/0000-0001-7548-1521/work/172102541en
dc.identifier.scopus85100258870en
dc.identifier.urihttps://hdl.handle.net/1885/733795354
dc.language.isoenen
dc.rightsPublisher Copyright: © The Royal Society of Chemistry 2020.en
dc.sourceJournal of Materials Chemistry Cen
dc.subjectIron-oxide nanoparticlesen
dc.subjectMetal nanoparticlesen
dc.subjectMediated synthesisen
dc.subjectSingleen
dc.subjectFunctionalizationen
dc.subjectCrystallineen
dc.subjectMaghemiteen
dc.subjectSilveren
dc.subjectSizeen
dc.titleSynthesis of gold-coated magnetic conglomerate nanoparticles with a fast magnetic response for bio-sensingen
dc.typeJournal articleen
dspace.entity.typePublicationen
local.bibliographicCitation.lastpage1043en
local.bibliographicCitation.startpage1034en
local.contributor.affiliationMehdipour, Milad; University of New South Walesen
local.contributor.affiliationGloag, Lucy; University of New South Walesen
local.contributor.affiliationBennett, Danielle T.; University of New South Walesen
local.contributor.affiliationHoque, Sharmin; University of New South Walesen
local.contributor.affiliationPardehkhorram, Raheleh; University of New South Walesen
local.contributor.affiliationBakthavathsalam, Padmavathy; University of New South Walesen
local.contributor.affiliationGoncales, Vinicius R.; University of New South Walesen
local.contributor.affiliationTilley, Richard D.; University of New South Walesen
local.contributor.affiliationGooding, J. Justin; University of New South Walesen
local.identifier.citationvolume9en
local.identifier.doi10.1039/d0tc04702cen
local.identifier.puref4c891e9-85a8-4f1a-b3e7-8548889d77f5en
local.identifier.urlhttps://www.scopus.com/pages/publications/85100258870en
local.identifier.urlhttps://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=anu_research_portal_plus2&SrcAuth=WosAPI&KeyUT=WOS:000612717600029&DestLinkType=FullRecord&DestApp=WOS_CPLen
local.type.statusPublisheden

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