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Automated data capture from free-text radiology reports to enhance accuracy of hospital inpatient stroke codes

dc.contributor.authorFlynn, Robert W.V.en
dc.contributor.authorMacdonald, Thomas M.en
dc.contributor.authorSchembri, Nicolaen
dc.contributor.authorMurray, Gordon D.en
dc.contributor.authorDoney, Alexander S.F.en
dc.date.accessioned2026-01-01T12:42:51Z
dc.date.available2026-01-01T12:42:51Z
dc.date.issued2010en
dc.description.abstractPurpose: Much potentially useful clinical information for pharmacoepidemiological research is contained in unstructured free-text documents and is not readily available for analysis. Routine health data such as Scottish Morbidity Records (SMR01) frequently use generic 'stroke' codes. Free-text Computerised Radiology Information System (CRIS) reports have potential to provide this missing detail. We aimed to increase the number of stroke-type-specific diagnoses by augmenting SMR01 with data derived from CRIS reports and to assess the accuracy of this methodology.  Methods: SMR01 codes describing first-ever-stroke admissions in Tayside, Scotland from 1994 to 2005 were linked to CRIS CT-brain scan reports occurring with 14 days of admission. Software was developed to parse the text and elicit details of stroke type using keyword matching. An algorithm was iteratively developed to differentiate intracerebral haemorrhage (ICH) from ischaemic stroke (IS) against a training set of reports with pathophysiologically precise SMR01 codes. This algorithm was then applied to CRIS reports associated with generic SMR01 codes. To establish the accuracy of the algorithm a sample of 150 ICH and 150 IS reports were independently classified by a stroke physician.  Results: There were 8419 SMR01 coded first-ever strokes. The proportion of patients with pathophysiologically clear diagnoses doubled from 2745 (32.6%) to 5614 (66.7%). The positive predictive value was 94.7% (95%CI 89.8-97.3) for IS and 76.7% (95%CI 69.3-82.7) for haemorrhagic stroke.  Conclusions: A free-text processing approach was acceptably accurate at identifying IS, but not ICH. This approach could be adapted to other studies where radiology reports may be informative.en
dc.description.statusPeer-revieweden
dc.format.extent5en
dc.identifier.issn1053-8569en
dc.identifier.otherPubMed:20602346en
dc.identifier.otherORCID:/0009-0008-5369-4663/work/199490770en
dc.identifier.scopus77956641332en
dc.identifier.urihttps://hdl.handle.net/1885/733800527
dc.language.isoenen
dc.sourcePharmacoepidemiology and Drug Safetyen
dc.subjectBrain infarctionen
dc.subjectCerebral haemorrhageen
dc.subjectMedical recordsen
dc.subjectNatural language processingen
dc.subjectRadiology information systemsen
dc.subjectStrokeen
dc.titleAutomated data capture from free-text radiology reports to enhance accuracy of hospital inpatient stroke codesen
dc.typeJournal articleen
dspace.entity.typePublicationen
local.bibliographicCitation.lastpage847en
local.bibliographicCitation.startpage843en
local.contributor.affiliationFlynn, Robert W.V.; University of Dundeeen
local.contributor.affiliationMacdonald, Thomas M.; University of Dundeeen
local.contributor.affiliationSchembri, Nicola; Medicines Monitoring Uniten
local.contributor.affiliationMurray, Gordon D.; University of Edinburghen
local.contributor.affiliationDoney, Alexander S.F.; University of Dundeeen
local.identifier.citationvolume19en
local.identifier.doi10.1002/pds.1981en
local.identifier.pure42a3bed0-d5df-404b-994f-6445a22202e3en
local.identifier.urlhttps://www.scopus.com/pages/publications/77956641332en
local.type.statusPublisheden

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