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Synthetic metallomolecules as agents for the control of DNA structure

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Date

2007-02-27

Authors

Richards, Adair D.
Rodger, Alison

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Research Projects

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Abstract

This tutorial review summarises B-DNA structure and metallomolecule binding modes and illustrates some DNA structures induced by molecules containing metallic cations. The effects of aquated metal ions, cobalt amines, ruthenium octahedral metal complexes, metallohelicates and platinum complexes such as cis-platin are discussed alongside the techniques of NMR, X-ray crystallography, gel electrophoresis, circular dichroism, linear dichroism and molecular dynamics. The review will be of interest to people interested in both DNA structure and roles of metallomolecules in biological systems.

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http://www.scopus.com/inward/record.url?scp=33847308169&partnerID=8YFLogxK
 https://hdl.handle.net/1885/733764817

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ANU Research Publications

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Chemical Society Reviews

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Journal article

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10.1039/b609495c

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