Morphological examination of complex microstructure via micro-CT imaging

Abstract

The benefits of tomography over traditional techniques for the characterization of three dimensional (3D) bone morphology and interconnectivity were discussed. Computer tomography (CT) were also used to study the structure of several biomaterials on the micron scale. Phase identification techniques were applied to binarize heterogeneous datasets for analysis and visualization. Extensive morphological analysis of the three-dimensional (3D) image data was taken using a range of morphological tools to quantify pore size distributions, volume orientation and topology. The results show that three dimensional measures were useful for characterizing bone regeneration and for correlating structure with bone properties.