Traumatic brain injury and long-term associations with work, divorce and academic achievement

dc.contributor.authorRytter, Hana Maláen
dc.contributor.authorHjorthøj, Carstenen
dc.contributor.authorGraff, Heidi Jeanneten
dc.contributor.authorEplov, Lene Falgaarden
dc.contributor.authorNordentoft, Mereteen
dc.contributor.authorBenros, Michael E.en
dc.contributor.authorErlangsen, Annetteen
dc.contributor.authorMadsen, Trineen
dc.date.accessioned2025-05-30T19:31:12Z
dc.date.available2025-05-30T19:31:12Z
dc.date.issued2024-07-05en
dc.description.abstractObjective: Traumatic brain injuries (TBI), irrespective of severity, may have long-term social implications. This study explores the relationships between TBI severity and outcomes related to work stability, divorce, and academic achievement.  Methods: Using a Danish nationwide sample of persons with and without TBI, we employed case-control and longitudinal cohort designs. The case-control design utilized individuals aged 18 to 60 years and examined work stability. Each case, employed at time of TBI, was compared with 10 matched controls. The cohort design utilized individuals alive from 1980 to 2016 with and without TBI and assessed the likelihood of 1) divorce and 2) higher-level education. TBI exposures included concussion, skull fractures, or confirmed TBI.  Results: TBI cases exhibited higher odds ratios (OR) for work instability at all follow-ups compared to controls. Increased TBI severity was associated with a higher risk of work instability at 2-year follow-up (concussion: OR = 1.83; skull fracture: OR = 2.22; confirmed TBI: OR = 4.55), and with a higher risk of not working at 10-year follow-up (confirmed TBI: OR = 2.82; concussion: OR = 1.63). The divorce incidence rate ratio (IRR) was elevated in individuals with TBI (males: IRR = 1.52; females: IRR = 1.48) compared to those without TBI. Individuals with childhood TBI had reduced chances of attaining high school degree or higher (males: IRR = 0.79; females: IRR = 0.85) compared to those without TBI.  Conclusion: TBI is associated with an increased long-term risk of social consequences, including work instability, divorce, and diminished chances of higher education, even in cases with concussion.en
dc.description.sponsorshipThe study was funded by The Danish Victim Foundation, grant number 19-610-00052 and Helse Foundation, grant number 19-B-0279. Further, the Danish Concussion Center also supported activities related to the study.en
dc.description.statusPeer-revieweden
dc.format.extent8en
dc.identifier.issn0091-7435en
dc.identifier.otherWOS:001267193900001en
dc.identifier.otherORCID:/0000-0003-3475-0558/work/169345366en
dc.identifier.scopus85197475160en
dc.identifier.urihttp://www.scopus.com/inward/record.url?scp=85197475160&partnerID=8YFLogxKen
dc.identifier.urihttps://hdl.handle.net/1885/733755361
dc.language.isoenen
dc.rightsPublisher Copyright: © 2024 The Authorsen
dc.sourcePreventive Medicineen
dc.subjectAcademic achievementen
dc.subjectConcussionen
dc.subjectMarital stabilityen
dc.subjectMild traumatic brain injuryen
dc.subjectNationwide register-based studyen
dc.subjectSocial consequencesen
dc.subjectTraumatic brain injuryen
dc.subjectWork instabilityen
dc.titleTraumatic brain injury and long-term associations with work, divorce and academic achievementen
dc.typeJournal articleen
dspace.entity.typePublicationen
local.contributor.affiliationRytter, Hana Malá; The Danish Concussion Centeren
local.contributor.affiliationHjorthøj, Carsten; Copenhagen Research Center for Mental Healthen
local.contributor.affiliationGraff, Heidi Jeannet; The Danish Concussion Centeren
local.contributor.affiliationEplov, Lene Falgaard; Copenhagen Research Center for Mental Healthen
local.contributor.affiliationNordentoft, Merete; Copenhagen Research Center for Mental Healthen
local.contributor.affiliationBenros, Michael E.; Copenhagen Research Center for Mental Healthen
local.contributor.affiliationErlangsen, Annette; Centre for Mental Health Research, National Centre for Epidemiology and Population Health, ANU College of Law, Governance and Policy, The Australian National Universityen
local.contributor.affiliationMadsen, Trine; Copenhagen Research Center for Mental Healthen
local.identifier.citationvolume185en
local.identifier.doi10.1016/j.ypmed.2024.108062en
local.identifier.pure5dd437b9-24c4-40c3-b826-b07dc6f4dd48en
local.identifier.urlhttps://www.scopus.com/pages/publications/85197475160en
local.type.statusPublisheden

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