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Saposin fold revealed by the NMR structure of NK-lysin

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Liepinsh, Edvards
Andersson, Mats
Ruysschaert, Jean Marie
Otting, Gottfried

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NK-Iysin is the first representative of a family of sequence related proteins -saposins, surfactant-associated protein B, pore forming amoeba proteins, and domains of acid sphingomyelinase, acyloxyacylhydrolase and plant aspartic proteinases-for which a structure has been determined.

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Nature Structural Biology

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