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Studies in macrolide synthesis: A sequential aldol/glycosylation approach to the synthesis of concanamycin A

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Paterson, Ian
McLeod, Malcolm D.

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The C19-C28 model fragment 2 of concanamycin A (1) was prepared by a Mukaiyama aldol reaction between silyl enol ether 11 and aldehyde 4 to give 7, followed by glycosylation with activated sugar 14 or 15.

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Tetrahedron Letters

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