Representation in the genome

dc.contributor.authorPridmore, Brant Layton
dc.date.accessioned2015-04-28T05:50:52Z
dc.date.available2015-04-28T05:50:52Z
dc.date.issued2013
dc.description.abstractMany biologists, and others, use representational talk to describe a range of genomic phenomena: ‘transcription’, ‘translation’, ‘the genetic code’ etc. How seriously we should take this depends on our account of representation. ‘Teleosemantics’ is an account that bases representational content on the functions of biological systems (‘devices’) that produce and consume physical tokens so as to communicate with one another and deal successfully with the world. On this view, many biological systems other than human beings display representational capacities. In particular, molecular genes within a cell, working with other cellular machinery, send messages to the ribosomes about what proteins to synthesise, how much and when. These messages are crucial to nearly all biological processes and, on a teleosemantic view, genuinely represent both the proteins that are to be synthesised and the environmental conditions with which those proteins are supposed to deal. It is tempting to think that a gene could also represent a trait —e.g. that the allele for yellow seeds in peas represents yellow seeds. The trouble is that there is no single consumer device to which the gene is sending a message. Most representation in the genome is fairly rudimentary but in some cases the genome displays more sophisticated capacities. Circadian clocks have evolved to represent future states of affairs and many viruses and bacteria practice genetic deception on host organisms. I also explore two attributes that are fundamental to the genome’s representational power: the compositionality of the parts that make it up and the arbitrariness of the genetic code that underpins the expression of molecular genes. Finally, I consider three ways of disputing the teleosemantic story about representation in the genome. First, are we obliged to say that representation is generated by functions deriving from inheritance systems other than the genome, hormonal inheritance systems, environmental niche construction, symbiosis etc? This is mostly an empirical matter and, in the current state of knowledge, the answer is largely in the negative. Second, is representational talk about the genome somehow second-rate: just a metaphor or an analogy or a useful model? In all three cases, my answer is ‘No’. Such worries boil down to worries about the teleosemantic story itself: they are not independent reasons to deny that the genome has representational capacities. Third, does according representational status to various nucleic acid structures do genuine conceptual work? Yes, it does. It improves the coherence of our theory of representation, presents a range of opportunities for further work, and has important implications for the way we see the kind of representation that human beings do.en_AU
dc.identifier.otherb3568382x
dc.identifier.urihttp://hdl.handle.net/1885/13343
dc.language.isoenen_AU
dc.subjectrepresentationen_AU
dc.subjectgenetic informationen_AU
dc.subjectmetaphoren_AU
dc.subjectteleosemanticsen_AU
dc.subjectteleonomyen_AU
dc.subjectMillikanen_AU
dc.subjectepigeneticsen_AU
dc.subjectbiological functionen_AU
dc.titleRepresentation in the genomeen_AU
dc.typeThesis (PhD)en_AU
dcterms.valid2014en_AU
local.contributor.affiliationSchool of Philosophy, The Australian National Universityen_AU
local.contributor.authoremailbpbp@iinet.net.auen_AU
local.contributor.supervisorSterelny, Kim
local.contributor.supervisorcontactkim.sterelny@anu.edu.auen_AU
local.identifier.doi10.25911/5d70f4361c389
local.mintdoimint
local.type.degreeDoctor of Philosophy (PhD)en_AU

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