Validation and recalibration of the Framingham cardiovascular disease risk models in an Australian Indigenous cohort: Does the current Framingham risk calculator accurately estimate true CVD risk for Indigenous Australians?

Abstract

In this study, we validated both the 1991 and 2008 Framingham CVD models using a cohort of Aboriginal and Torres Strait Islander adults drawn from remote Indigenous communities in Far North Queensland. Recalibration was also conducted to help generate more accurate CVD risk predictions for this population. Finally, we developed a CVD risk chart that could help improve the assessment and management of CVD in the Australian Indigenous population, particularly those in remote regions of Australia.