Structural basis for the light regulation of chloroplast NADP malate dehydrogenase
The activity of chloroplast NADP-malate dehydrogenase (NADP-MDH; EC 126.96.36.199) in both C3 and C4 plants is regulated by light intensity. In darkness, the activity of the enzyme can be less than 1% of the maximal activity found at high light intensities. The extent of activation in the light is dynamic, responding rapidly to changes in light intensity and adapting to changes in photosynthetic rate. Enzyme activation is caused by thioredoxin-catalyzed reduction of two regulatory disulfide bonds,...[Show more]
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