A novel β-oxa polyunsaturated fatty acid downregulates the activation of the IκB kinase/nuclear factor κB pathway, inhibits expression of endothelial cell adhesion molecules, and depresses inflammation
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Ferrante, Antonio; Robinson, Brenton S; Singh, Harmeet; Jersmann, Herbertus; Ferrante, Judith V; Huang, Zhi H; Trout, Neil A; Pitt, Michael J; Rathjen, Deborah A; Easton, Christopher; Poulos, Alf; Prager, Rolf H; Lee, Frank S; Hii, Charles
Description
Several novel polyunsaturated fatty acids (PUFAs) that contain either an oxygen or sulfur atom in the β-position were found to exhibit more selective antiinflammatory properties than their natural PUFA counterparts. One of these, β-oxa-23:4n-6, unlike n
| Collections | ANU Research Publications |
|---|---|
| Date published: | 2006 |
| Type: | Journal article |
| URI: | http://hdl.handle.net/1885/84977 |
| Source: | Circulation Research |
| DOI: | 10.1161/01.RES.0000231292.66084.cd |
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| File | Description | Size | Format | Image |
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| 01_Ferrante_A_novel_β-oxa_polyunsaturated_2006.pdf | 314.94 kB | Adobe PDF | Request a copy |
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