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The Pathophysiology of Serotonin Toxicity in Animals and Humans

Isbister, Geoffrey K; Buckley, Nicholas


Serotonin toxicity (or serotonin syndrome) has become an increasingly common and important clinical problem in medicine over the last 15 years with the introduction of many new antidepressants that can cause increased levels of serotonin (5-HT) in the central nervous system (CNS). Severe and life-threatening cases are almost exclusively a result of combinations of antidepressants (usually monoamine oxidase inhibitors and selective serotonin reuptake inhibitors). Unfortunately, the term...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
Source: Clinical Neuropharmacology
DOI: 10.1097/01.wnf.0000177642.89888.85


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