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Essential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-kB in B cell clonal anergy

Blery, Mathieu; Tze, Lina; Miosge, Lisa; Jun, Jesse; Goodnow, Christopher

Description

Divergent hypotheses exist to explain how signaling by the B cell receptor (BCR) is initiated after antigen binding and how it is qualitatively altered in anergic B cells to selectively uncouple from nuclear factor κB and c-Jun N-terminal kinase pathways

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
URI: http://hdl.handle.net/1885/78666
Source: Journal of Experimental Medicine
DOI: 10.1084/jem.20060552

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