Essential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-kB in B cell clonal anergy
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Blery, Mathieu; Tze, Lina; Miosge, Lisa; Jun, Jesse; Goodnow, Christopher
Description
Divergent hypotheses exist to explain how signaling by the B cell receptor (BCR) is initiated after antigen binding and how it is qualitatively altered in anergic B cells to selectively uncouple from nuclear factor κB and c-Jun N-terminal kinase pathways
Collections | ANU Research Publications |
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Date published: | 2006 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/78666 |
Source: | Journal of Experimental Medicine |
DOI: | 10.1084/jem.20060552 |
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01_Blery_Essential_role_of_membrane_2006.pdf | 2.69 MB | Adobe PDF | Request a copy |
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