Skip navigation
Skip navigation

Roles of Notch and NF-kB signaling in allogeneic responses

Murase, Tosei

Description

The induction of robust allograft tolerance is the ultimate goal for clinical transplantation. Although studies have identified that dendritic cells (DCs) are important for induction of antigen-specific tolerance, the requirements for generating tolerogenic DCs are yet to be elucidated. Recently, it has been demonstrated the modulation of two signaling pathways, Notch and nuclear factor KB (NF-KB) can render DCs tolerogenic. The studies documented here examine (1) whether immature DCs...[Show more]

CollectionsOpen Access Theses
Date published: 2011-04-07
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/7166

Download

File Description SizeFormat Image
Murase-front.pdffront pages1.21 MBAdobe PDFThumbnail
Murase-whole.pdfwhole thesis21.27 MBAdobe PDFThumbnail


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  23 August 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator