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Cyclization of the intrinsically disordered α 1S dihydropyridine receptor II-III loop enhances secondary structure and in vitro function

Tae, Han Shen; Cui, Yan Fang; Karunasekara, Yamuna; Board, Philip; Dulhunty, Angela; Casarotto, Marco


A key component of excitation contraction (EC) coupling in skeletal muscle is the cytoplasmic linker (II-III loop) between the second and third transmembrane repeats of the α1S subunit of the dihydropyridine receptor (DHPR). The II-III loop has been prev

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
Source: Journal of Biological Chemistry
DOI: 10.1074/jbc.M110.205476
Access Rights: Open Access


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