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Selective 15 N-labeling of the side-chain amide groups of asparagine and glutamine for applications in paramagnetic NMR spectroscopy

Cao, Chan; Chen, Jia-Liang; Yang, Yin; Huang, Feng; Su, Xuncheng; Otting, Gottfried

Description

The side-chain amide groups of asparagine and glutamine play important roles in stabilizing the structural fold of proteins, participating in hydrogen-bonding networks and protein interactions. Selective 15N-labeling of side-chain amides, however, can be

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
URI: http://hdl.handle.net/1885/63567
Source: Journal of Biomolecular NMR
DOI: 10.1007/s10858-014-9844-0

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