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Synthesis of hexa aza cages, SarAr-NCS and AmBaSar and a study of their metal complexation, conjugation to nanomaterials and proteins for application in radioimaging and therapy

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Mume, Eskender; Asad, Ali; Di Bartolo, Nadine; Kong, Linggen; Smith, Christopher M; Sargeson, Alan; Price, Roger; Smith, Suzanne

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A novel hexa aza cage, N1-(4-isothiocyanatobenzyl)-3,6,10,13,16, 19-hexaazabicyclo[6.6.6]icosane-1,8-diamine (SarAr-NCS) was synthesized in good yield and characterized by 1H NMR and electrospray mass spectrometry. A new method for the synthesis of the re

dc.contributor.authorMume, Eskender
dc.contributor.authorAsad, Ali
dc.contributor.authorDi Bartolo, Nadine
dc.contributor.authorKong, Linggen
dc.contributor.authorSmith, Christopher M
dc.contributor.authorSargeson, Alan
dc.contributor.authorPrice, Roger
dc.contributor.authorSmith, Suzanne
dc.date.accessioned2015-12-10T23:04:37Z
dc.identifier.issn1477-9226
dc.identifier.urihttp://hdl.handle.net/1885/62450
dc.description.abstractA novel hexa aza cage, N1-(4-isothiocyanatobenzyl)-3,6,10,13,16, 19-hexaazabicyclo[6.6.6]icosane-1,8-diamine (SarAr-NCS) was synthesized in good yield and characterized by 1H NMR and electrospray mass spectrometry. A new method for the synthesis of the re
dc.publisherRoyal Society of Chemistry
dc.sourceDalton Transactions
dc.subjectKeywords: Electrospray mass spectrometry; Entry point; Immunoreactivities; Lyophilized powders; Metal complexation; PET imaging; Radiolabeling; Silica particles; Amines; Antibodies; Cobalt compounds; Ligands; Silica; Zinc; Copper compounds
dc.titleSynthesis of hexa aza cages, SarAr-NCS and AmBaSar and a study of their metal complexation, conjugation to nanomaterials and proteins for application in radioimaging and therapy
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume42
dc.date.issued2013
local.identifier.absfor030201 - Bioinorganic Chemistry
local.identifier.ariespublicationu4005981xPUB700
local.type.statusPublished Version
local.contributor.affiliationMume, Eskender, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationAsad, Ali, Sir Charles Gairdner Hospital Perth
local.contributor.affiliationDi Bartolo, Nadine, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationKong, Linggen, Australian Nuclear Science and Technology Organization
local.contributor.affiliationSmith, Christopher M, Australian Nuclear Science and Technology Organisation
local.contributor.affiliationSargeson, Alan, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationPrice, Roger, Sir Charles Gairdner Hospital, Perth
local.contributor.affiliationSmith, Suzanne, College of Physical and Mathematical Sciences, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.issue40
local.bibliographicCitation.startpage14402
local.bibliographicCitation.lastpage14410
local.identifier.doi10.1039/c3dt51199e
local.identifier.absseo970103 - Expanding Knowledge in the Chemical Sciences
dc.date.updated2016-02-24T10:25:55Z
local.identifier.scopusID2-s2.0-84884695251
CollectionsANU Research Publications

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