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Urinary alkalinisation for acute chlorophenoxy herbicide poisoning

Roberts, Darren; Buckley, Nicholas


Background: Acute poisoning with chlorophenoxy herbicides (such as 2,4-D, MCPA, 2,4,5-T and mecoprop) is reported worldwide, potentially causing severe toxicity and death in exposed patients. Animal studies support the application of urinary alkalinisation (particularly using sodium bicarbonate) in the management of acute chlorophenoxy herbicide poisoning to facilitate excretion of these herbicides. Some case reports of human exposure have suggested benefit from urinary alkalinisation also....[Show more]

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
Source: Cochrane Database of Systematic Reviews (CDSR)
DOI: 10.1002/14651858.CD005488.pub2


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