The identification of new metallo-β-lactamase inhibitor leads from fragment-based screening
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Vella, Peter; Hussein, Waleed M; Leung, Eleanor W W; Clayton, Daniel; Ollis, David; Mitic, Natasa; Schenk, Gerhard; McGeary, Ross Peter
Description
The emergence of metallo-β-lactamases (MBLs) capable of hydrolysing a broad spectrum of β-lactam antibiotics is particularly concerning for the future treatment of bacterial infections. This work describes the discovery of lead compounds for the develop
| Collections | ANU Research Publications |
|---|---|
| Date published: | 2011 |
| Type: | Journal article |
| URI: | http://hdl.handle.net/1885/58869 |
| Source: | Bioorganic and Medicinal Chemistry Letters |
| DOI: | 10.1016/j.bmcl.2011.04.027 |
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| File | Description | Size | Format | Image |
|---|---|---|---|---|
| 01_Vella_The_identification_of_new_2011.pdf | 376.28 kB | Adobe PDF | Request a copy |
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