The region homologos to the X-chromosome inactivation centre has been disrupted in marsupial and monotreme mammals
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Hore, Tim; Koina, Edda; Wakefield, Matthew; Graves, Jennifer
Description
Marsupial, as well as eutherian, mammals are subject to X chromosome inactivation in the somatic cells of females, although the phenotype and the molecular mechanism differ in important respects. Monotreme mammals appear to subscribe at least to a form of dosage compensation of X-borne genes. An important question is whether inactivation in these non-eutherian mammals involves co-ordination by a control locus homologous to the XIST gene and neighbouring genes, which play a key regulatory role...[Show more]
Collections | ANU Research Publications |
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Date published: | 2007 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/56956 |
Source: | Chromosome Research |
DOI: | 10.1007/s10577-007-1119-0 |
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01_Hore_The_region_homologos_to_the_2007.pdf | 5.21 MB | Adobe PDF | Request a copy |
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