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The total synthesis of (-)-tetrahydrolipstatin

Bodkin, Jennifer A; Humphries, Edward; McLeod, Malcolm

Description

Careful control during the bromolactonization of β,γ-unsaturated acid (4) was required to regioselectivity afford the trans-β-lactone (3) as the major diastereomer. Radical debromination of (3) followed by a three-step sequence of reactions afforded th

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
URI: http://hdl.handle.net/1885/53293
Source: Australian Journal of Chemistry
DOI: 10.1071/CH03121

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