The total synthesis of (-)-tetrahydrolipstatin
Careful control during the bromolactonization of β,γ-unsaturated acid (4) was required to regioselectivity afford the trans-β-lactone (3) as the major diastereomer. Radical debromination of (3) followed by a three-step sequence of reactions afforded th
|Collections||ANU Research Publications|
|Source:||Australian Journal of Chemistry|
|01_Bodkin_The_total_synthesis_of_2003.pdf||232.92 kB||Adobe PDF||Request a copy|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.