Oral folic acid and vitamin B-12 supplementation to prevent cognitive decline in community-dwelling older adults with depressive symptoms-the Beyond Ageing Project: a randomized controlled trial
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Walker, Janine; Batterham, Philip; Mackinnon, Andrew; Jorm, Anthony F; Hickie, Ian B; Fenech, Michael; Kljakovic, Marjan; Crisp, Dimity; Christensen, Helen
Description
Background: Evidence remains unclear as to whether folic acid (FA) and vitamin B-12 supplementation is effective in reducing depressive symptoms. Objectives: The objective was to determine whether oral FA + vitamin B-12 supplementation prevented cognitive decline in a cohort of community-dwelling older adults with elevated psychological distress. Design: A randomized controlled trial (RCT) with a completely crossed 2 x 2 x 2 factorial design comprising daily oral 400 μg FA + 100 μg vitamin B-12...[Show more]
Collections | ANU Research Publications |
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Date published: | 2012 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/52590 |
Source: | American Journal of Clinical Nutrition |
DOI: | 10.3945/ajcn.110.007799 |
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File | Description | Size | Format | Image |
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01_Walker_Oral_folic_acid_and_vitamin_2012.pdf | 35.49 kB | Adobe PDF | Request a copy | |
02_Walker_Oral_folic_acid_and_vitamin_2012.pdf | 287.17 kB | Adobe PDF | Request a copy |
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