Impact of Meningococcal B (4CMenB) Vaccine on Pharyngeal Neisseria meningitidis Carriage Density and Persistence in Adolescents
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McMillan, Mark; Walters, Luke; Sullivan, Thomas; Leong, Lex E X; Turra, Mark; Lawrence, Andrew; Koehler, Ann P; Finn, Adam; Andrews, Ross; Marshall, Helen
Description
Background Higher density of Neisseria meningitidis carriage may be associated with transmission of the meningococcus. Our aim was to establish the impact of meningococcal B (4CMenB) vaccine on N. meningitidis carriage density. Methods We compared 4CMenB vaccine to control among 913 South Australian students aged approximately 15–18 years in a cluster randomized trial who had N. meningitidis carriage at 12 months. Oropharyngeal swabs were collected at baseline and 12 months later to detect...[Show more]
Collections | ANU Research Publications |
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Date published: | 2021 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/311783 |
Source: | Clinical Infectious Diseases |
DOI: | 10.1093/cid/ciaa610 |
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