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Bacteria-based cancer immunotherapy: A re-emerging strategy with contemporary implications

Almonte, Andrew

Description

Immunotherapy is a re-emerging alternative to other invasive and debilitating cancer treatments. Monoclonal antibodies that disrupt immune checkpoint molecules, such as programmed cell death protein 1 (PD1) or cytotoxic T-lymphocyte-associated protein 4 (CTLA4), have been paradigm-shifting advances in medical oncology. However, therapy response rates need improvement, and important questions remain regarding the mechanisms by which checkpoint therapies promote their therapeutic effects. One...[Show more]

CollectionsOpen Access Theses
Date published: 2023
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/303383
DOI: 10.25911/DNAR-RV79

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