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Immunomodulatory and antiangiogenic mechanisms of polymolecular botanical drug extract C5OSEW5050ESA OS derived from orthosiphon stamineus

Al-Suede, Fouad Saleih R; Ahamed, Mohamed B. Khadeer; Abdul Majid, Aman Shah; Mohammed Saghir, Sultan Ayesh; Oon, Chern Ein; Abdul Majid, Amin Malik Shah Bin


Nuvastatic is a polymolecular botanical drug formulation containing a proprietary extract of a selected cultivar of Orthosiphon stamineus (OS) code name, C5OSEW5050ESA OS. The anti-angiogenic activity of C5OSEW5050ESA OS was explored by evaluating its activity towards a variety of angiogenesis modulators in vitro and in vivo. Multiplex immunoassays reveals that C5OSEW5050ESA OS inhibits Vascular Endothelial Growth factor (VEGF), Epidermal Growth Factor (EGF), Fibroblast Growth Factor (FGF),...[Show more]

CollectionsANU Research Publications
Date published: 2021
Type: Journal article
Source: Journal of Angiotherapy
DOI: 10.25163/angiotherapy.51211411913130321
Access Rights: Open Access


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