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Limitations with in vitro production of dendritic cells using cytokines

O'Neill, Helen; Wilson, Heather L


Dendritic cells (DC) are the most effective antigen-presenting cells. Many studies now show that DC can be generated in vitro from a number of starting cell populations containing hematopoietic precursors. The protocols used involve different combinations of cytokines including granulocyte macrophage-colony stimulating factor (GM-CSF), which supports myeloid precursors, or interleukin-7, which supports lymphoid precursors. DC are commonly generated by in vitro culture of bone marrow or...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
Source: Journal of Leukocyte Biology
DOI: 10.1189/jlb.0903446


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