consensusDE: an R package for assessing consensus of multiple RNA-seq algorithms with RUV correction
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Waardenberg, Ashley J.; Field, Matthew
Description
Extensive evaluation of RNA-seq methods have demonstrated that no single algorithm consistently outperforms all others. Removal of unwanted variation (RUV) has also been proposed as a method for stabilizing differential expression (DE) results. Despite this, it remains a challenge to run multiple RNA-seq algorithms to identify significant differences common to multiple algorithms, whilst also integrating and assessing the impact of RUV into all algorithms. consensusDE was developed to...[Show more]
Collections | ANU Research Publications |
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Date published: | 2019 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/282686 |
Source: | PeerJ |
DOI: | 10.7717/peerj.8206 |
Access Rights: | Open Access |
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peerj-8206.pdf | 2.68 MB | Adobe PDF |
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