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What's where and why at a vascular myoendothelial microdomain signalling complex

Sandow, Shaun, L; Haddock, Rebecca; Hill, Caryl; Chadha, Preet S; Kerr, Paul M; Welsh, Donald G; Plane, Frances


1. Modulation of vascular cell calcium is critical for the control of vascular tone, blood flow and pressure. 2. Specialized microdomain signalling sites associated with calcium modulation are present in vascular smooth muscle cells, where spatially localized channels and calcium store receptors interact functionally. Anatomical studies suggest that such sites are also present in endothelial cells. 3. The characteristics of these sites near heterocellular myoendothelial gap junctions (MEGJs)...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Clinical and Experimental Pharmacology and Physiology
DOI: 10.1111/j.1440-1681.2008.05076.x


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