Levodopa inhibits the development of lens-induced myopia in chicks
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Thomson, Kate; Morgan, Ian; Karouta, Cindy; Ashby, Regan
Description
Animal models have demonstrated a link between dysregulation of the retinal dopamine system and the development of myopia (short‑sightedness). We have previously demonstrated that topical application of levodopa in chicks can inhibit the development of form‑deprivation myopia (fDM) in a dose‑dependent manner. Here, we examine whether this same protection is observed in lens‑induced myopia (LiM), and whether levodopa’s protection against fDM and LiM occurs through a dopamine D1- or D2-like...[Show more]
Collections | ANU Research Publications |
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Date published: | 2020 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/258299 |
Source: | Scientific Reports |
DOI: | 10.1038/s41598-020-70271-z |
Access Rights: | Open Access |
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01_Thomson_Levodopa_inhibits_the_2020.pdf | 1.79 MB | Adobe PDF |
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