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Protein engineering: the potential of remote mutations

Wilding, Matthew; Hong, Nansook; Spence, Matthew; Buckle, Ashley; Jackson, Colin


Engineered proteins, especially enzymes, are now commonly used in many industries owing to their catalytic power, specific binding of ligands, and properties as materials and food additives. As the number of potential uses for engineered proteins has increased, the interest in engineering or designing proteins to have greater stability, activity and specificity has increased in turn. With any rational engineering or design pursuit, the success of these endeavours relies on our fundamental...[Show more]

CollectionsANU Research Publications
Date published: 2019
Type: Journal article
Source: Biochemical Society Transactions
DOI: 10.1042/BST20180614


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