Sherburn, Michael; George, Josemon
Readily available and stable substituted -
dendralenes undergo highly chemo-, regio-, diastereo-, and
enantioselective organocatalyzed Diels−Alder reactions with
acrolein to form enantiomerically enriched cycloadducts.
These monocycloadducts carry semicyclic dienes that undergo
a second, substrate-controlled diastereoselective Diels−Alder
reaction with a different dienophile to form 2-fold cycloadducts. Overall, annulated, functional group rich, chiral Δ1(9)-
octalin building blocks...[Show more]
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