The structure, dynamics, function and evolution of binding proteins
Macromolecular recognition - the ability of biological molecules (especially proteins) to produce physiological responses by forming specific, high-affinity, non-covalent complexes with other molecules - underlies every biological process, including cellular signalling, immune recognition and enzyme catalysis. Determining the chemical and physical factors (including the structure and dynamics of the interacting molecules) that govern the properties of macromolecular recognition events is...[Show more]
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