Assessing the influence of solar ultraviolet radiation exposure on the primary immune response to immunisation with a protein antigen in humans
Ultraviolet radiation (UVR) is immunosuppressive, particularly to antigen-specific cell-mediated processes, acting via direct and indirect (e.g. vitamin D-mediated) pathways. This research aimed to examine the influence of acute and cumulative solar UVR exposure, at doses relevant to day-to-day activities, on the primary immune response to immunisation in humans. The Australian Ultraviolet Radiation and Immunity (AusUVI) Study was a prospective, longitudinal, twin-centre immunotoxicological...[Show more]
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